Anti-Inflammatory Diet

All health care starts with diet. My recommendations for a healthy diet are here:
Anti-Inflammatory Diet and Lifestyle.
There are over 190 articles on diet, inflammation and disease on this blog
(find topics using search [upper left] or index [lower right]), and
more articles by Prof. Ayers on Suite101 .

Tuesday, May 27, 2014

Metformin, Antibiotic with Autoimmune Side Effects

----The other 200 posts are here----
Metformin
Major points linked in this article:
  • Metformin is commonly used in the treatment of diabetes.
  • Metformin is structurally and chemically related to arginine, guanine and Canavanine.
  • Side effects of Metformin include GI upset and autoimmune lupus (same with Canavanine.)
  • Metformin also kills bacteria, i.e. it is an antibiotic.
  • Many pharmaceuticals, e.g. statins, were first identified as antibiotics produced by fungi.
  • Antibiotics select for antibiotic resistance genes, i.e. essential bacterial genes that have mutated to no longer be inactivated by antibiotics.
  • New antibiotic resistance genes are combined with other resistance genes on multiple resistance plasmids that are transferred as a group.
  • Because of its wide use, resistance to Metformin (and statins) as an antibiotic probably already exists and has been incorporated into multiple drug resistance plasmids.
  • Many common pharmaceuticals are also antibiotics and probably select for multiple drug resistance.
  • A major contributor to multiple drug resistance, “super bugs”, and the rapid loss of efficacy of antibiotics is the over use of pharmaceuticals in general, in addition to the specific abuse of antibiotics designed to kill pathogens.
Metformin is a Good Anti-Diabetic, but...
Arginine
Metformin is the treatment of choice for type 2 diabetes and yet, like many other common drugs, the full extent of its impact on the body (and the body’s essential microbiome of bacteria and fungi) has not been studied.  This article should not be seen as a criticism of the pharmacological efficacy of Metformin in lowering blood sugar.  The point here is that Metformin alters gut flora and its major pharmacological impact may result from alteration of the gut flora and not direct action on cells of body organs.  Metformin, because of its structure and size would be expected to act relatively indiscriminately in numerous cell functions, but I don't think that these interactions are as important as the impact on gut flora.  Metformin has all of the properties of an antibiotic selected to lower blood sugar and have limited side effects.  It would not be expected to cause a dramatic increase in autoimmunity, because diabetics already have elevated autoimmunity and associated deficiencies in gut flora.

Metformin is a Diguanide
 I previously explored the interesting properties of Metformin in my laboratory and through computer modeling experiments, and found it would react with many cellular enzymes and receptors similarly to the amino acid arginine.  This was no surprise, since the working end of arginine is a guanide and Metformin is a Siamese twin of guanides, i.e. a biguanide.  I might as well also say that another guanide, Canavanine, a toxic, antimicrobial phytoalexin in bean sprouts, has similar properties.
Canavanine

Phytochemicals as Antibiotics


  
I have studied (and written about) the natural plant antibiotics, phytoalexins, in legumes, and particularly in soy beans, so I would expect all of the chemicals, (a.k.a. phytochemicals or “antioxidants”) extracted from plants, e.g. alkaloids, polyphenols and essential oils, to kill bacteria and be toxic to human cells.  The selective advantage to plants in producing phytochemicals is the antibiotic activity of those chemicals.  Pathogens that have adapted for growth on one species of plant have resistance genes to that plant’s phytoalexins.  Thus, bacterial genes for resistance to the antibiotic activity of drugs derived from phytochemicals are common in nature and broad use of these drugs merely selects for the transfer of these genes to gut flora.
Canavanine and Lupus
What put together more pieces of the gut flora/antibiotic/autoimmune disease puzzle for me, was coming across Dr. Loren Cordain's recent reiteration of the toxicity of legumes and his singular example of Canavanine from alfalfa sprouts as a contributor to the autoimmune disease, lupus.  When I looked up the structure of Canavanine and found it to be a guanide, I immediately started making comparisons to Metformin and was amazed to see that these chemicals share the same list of side effects focused on the gut.  Moreover, lupus is also a side effect of both Metformin and Canavanine.  It was initially surprising, that a recent study suggests that the anti-diabetic action of Metformin may result indirectly from its antibiotic effects on gut flora.  I now expect that Canavanine causes lupus by killing or altering the metabolism of particular species of bacterial gut flora involved in the normal functions of the immune system, e.g. Tregs required for immune tolerance.  It is now a common observation that many pharmaceuticals act indirectly via their impact on gut flora, i.e. many pharmaceuticals are fundamentally antibiotics, and particular antibiotics can duplicate the activity of pharmaceuticals.
Pharmaceuticals Select for Multiple Antibiotic Resistance
I have one other concern about the wide use of drugs derived from phytoalexins.  Metformin can be considered one of those drugs, and just like phytoalexins, it is a potent antibiotic.  There is no difference between purified natural plant antibiotics/ phytoalexins/ polyphenols/ antioxidants and commercially synthesized antibiotics with respect to selecting for resistance.  I would expect that resistance to Metformin, as an antibiotic, has already developed in common gut flora and consequently, that multiple drug resistance plasmids from hospital pathogens now contain Metformin resistance.  Thus, I would also expect Metformin and many other pharmaceuticals to select for multiple antibiotic resistance. [An additional example is the antibiotic activity of NSAIDs on Helicobacter pylori.  I think that prevalent use of NSAIDs in many countries is responsible for the decline in H. pylori.]



72 comments:

Unknown said...

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117136/

"Metformin is an anti-oxidant that is routinely used to treat diabetic patients. Metformin exerts its potent anti-oxidant effect by inhibiting mitochondrial complex I, thereby preventing mitochondrial ROS production and mitochondrial oxidative phosphorylation. Thus, metformin functions as a “weak” mitochondrial poison."

David said...

Just want to say I really enjoy this blog and please keep the posts coming.
I was wondering if your opinions had changed regarding lectins/wga/ legumes and autoimmunity? Previously (2008/9) your posts indicate that these are safe to eat and don't have the potential to leave the gut.
Has your opinion changed? (Given the link to Dr. Cordains) blog?
Thanks in advance!

Lisa said...

May I suggest that you also look into the effects of Metformin on mitochondria? Here is an article on that topic - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133963/

Here is another interesting article about Metformin - http://www.hormonesmatter.com/pcos-pregnancy-metformin-and-vitamin-b12-deficiency/

Gretchen said...

Art. I enjoy your blog and noticed you got your PhD at U Colorado, working with plants. I was wondering if you know Peter Albersheim. I was his first grad student and visited him recently.

I can't find contact information for you. If you reply, you can find my contact info at http://wildlyfluctuating.blogspot.com/

steve said...

As a diabetologist, metformin is one of the only oral medications that I still have any faith in. Maybe, I’m wrong, but its hard to argue against the improvements in blood sugars that we see with it, not to mention other peripheral benefits such as improved lipid profiles and weight loss. One would speculate that if it did have a clinically significant antibiotic effect, we would see the opposite resulting from dysbiosis. New onset autoimmune conditions associated with metformin are extremely rare and if anything, the evidence might suggest that it may be beneficial. A pubmed search for “metformin and autoimmune” provides a good sampling of studies to review showing potential benefits. I respect your opinion, so would love to explore this issue more….thanks for your insight!

Dr. Art Ayers said...

Charles,
I addressed the promiscuous interaction of Metformin with many enzymes and would expect activity in many different in vitro assays. The statement quoted is just a summary of thoughts not represented by data presented in the paper.

Even if the in vitro concepts were relevant, the fact remains that Metformin and most other drugs also act as antibiotics and will impact drug resistance.

Thanks for the comment.

Dr. Art Ayers said...

David,
I am familiar with lectins and how they work, since I am a glycobiologist, but I think that our gut is adapted to minimize the impact of eaten (especially cooked) lectins. I still don't think that plants were adapted to be eaten and therefore should be eaten with care. I still don't understand why gluten is so dangerous, but I think that we haven't evaluated the impact of its polyglutamines.

Thanks for the comments.

Dr. Art Ayers said...

Steve,
I have altered my text to make it clear that I am not maligning Metformin, but merely pointing out that it acts in the gut as an antibiotic. One would expect in diabetics who already have damaged gut flora that are adapted to other pharmaceuticals and are already displaying autoimmune symptoms, that only moderate gut disturbance would be observed taking Metformin. That is what is observed and as resistance increases, disturbance abates.

I am not trying to change or criticize the use of Metformin in clinical settings. I merely want to point out that pharmaceuticals alter gut flora and could be responsible for accumulation of multiple drug resistance due to their prevalent, studied antibiotic activities.

Are you claiming that diabetics don't have an increased risk of autoimmune disease or that some antibiotics don't reduce symptoms of autoimmune disease?

Thanks for your comments.

David said...

Thanks for the response. I was wondering if you would mind commenting on nightshades as Dr. Cordain also feels they are damaging.
Finally, whats your thoughts on eggs and the proteases the whites contain.
Apologies for the multiple questions!

Anonymous said...

Are statins really antibiotics? Was wondering if you had any resources for more information on that. Thanks!

Dr. Art Ayers said...

Ingrid,
Yes, the first statin was purified from a mixture of chemicals produced by a fungus, which tested positive for inhibition of an enzyme involved in cholesterol synthesis. The selective advantage for the fungus to produce the compound in the first place was to kill bacteria. Subsequent testing for antibiotic activity confirmed that.
Numerous studies can be found via a Google search for:
"antibiotic activity of statins"

Once again. It is widely known in the pharmaceutical industry that most drugs have significant antibiotic activity on gut flora. Moreover, it is problematical that most pharmaceutically relevant activity results from the differential antibiotic effects on gut flora. This is true for anti-diabetics and statins.

Thanks for your questions.

Raj said...
This comment has been removed by the author.
Anonymous said...

Statins are antibiotics, see here:
http://en.wikipedia.org/wiki/Statin#Available_forms

Some reading on statin discovery here:
http://www.zoeharcombe.com/2013/10/how-statin-drugs-really-lower-cholesterol-and-kill-you-one-cell-at-a-time/

Now there must be a difference between permanent treatment by taking for instance Lovastating pills (killing bugs and blocking the cholesterol production pathway) and occasional eating of oyster mushrooms (killing some bugs, feeding others with beneficial glukans).

Natasha T. said...

Dear Dr. Ayers,

Hi! I am really enjoying your blog. Excellent research!

I have just finished reading Blaser's "Missing Microbes" and Velasquez-Manoff's "Epidemic of Absence". And, I monitor FTA and AnimalPharm.

I am a little overwhelmed about where to start and how to apply all of this information to myself and my husband.

Regarding myself, age 40, born naturally but *not* breastfed (soy formula). I am not aware of an antibiotics until I was 11 - my Mom was trying to do things healthy. So, antibiotics at age 11, age 17 and then again age 39. Each time period - I now realize - coincided with major weight gains. Age 11 (40 pounds), age 17 (105 pounds over two years), age 39 (15 pounds). Age 17 was a simple surgery but I was given intravenous anti-biotics - it took me 10 years to recover my health from this surgery, another couple of years to lose the 100 pounds. I was diagnosed CFS/ME/chemical sensitivity. I currently have food and pollen allergies (terrible this year). As you can imagine, I also had terrible periods and starting at 11 and only normalized a few years ago after lots of alternative treament.

I have started FTA's protocol with resistant starch and SBO's. What else can I do? Is there any specific gut bug that I should focus on, considering I never had breast milk and thus had a limited microbiome to start with?

My husband is T1-diabetic (auto immune). Last year he was struck by another auto immune illness (Sarcoidosis). Fortunately, it only attacked his lungs and not his heart. However, he is still doing poorly (extremely fatigued). No allergies. No gluten issues.

What do you think of the parasite solution? Would he benefit? He has *not* taken SBO (yet).

My general health is OK, but I am so tired of being fat. Especially because I managed to lose that 100+ weight gain (low cal, paleo type diet). In the past year I have done low calorie, low carb, low carb high fat, Dr. Eades diet too, and now switching to anti-inflammatory diets. No matter what, my recently higher weight (195 pounds at 5/6") won't shift at all. Sorry to be shallow, but I have worked so hard and "know" what to do to lose...and its not working.

Advice? Thank you! Natasha

Dr. Art Ayers said...

Natasha,
It seems that all members of your family have damaged gut flora. The Anti-Inflammatory Diet that I outline should be all of the diet recommendations that you need. The remainder is to add the bacterial species that you are missing.

Health requires 1) diet, 2) exercise and 3) gut flora

Diet changes will have no impact without adding back missing bacteria.

I have a hundred articles on this general subject.

I agree for you to start resistant starch plus a probiotic with Clostridium butyricum.

I think that everyone should learn to ferment their own vegetables with just salt and natural bacteria (not commercial cultures, because I think most are missing the right bacteria to supplement gut flora.)

With your autoimmune symptoms, you are probably also vitamin D deficient. Supplement (10K D3) and check your serum levels. Check Mark's Daily Apple for carb levels with a paleo diet, and Animal Pharm for parasite info.

Remember that fat cells cause inflammation, so you may have to add additional omega-3 to further suppress inflammation.

I think that inflammation causes obesity and obesity produces inflammation. In both cases, the gut flora are mediated the action. I think that the whey shakes in the Drs. Eades diet that I have discussed, can impact gut flora and change the eating behavior associated with obesity.

Thanks for your questions. Keep me updated.

Tim Steele said...

Hi, Art - Still trying to wrap my head around antibiotic resistance. Does having a large population of gut bugs that are resistant to the effects of Metformin, or any antibiotic for that matter, effect the function of the biome?

Or is your concern mainly that Metformin will kill off a large group of microbes that will never return to pre-Metformin levels?

Dr. Art Ayers said...

Tim,
The importance of the antibiotic activity of common drugs is that activity selects for corresponding bacterial mutants that are resistant. Any bacterium that picks up the new resistance gene will be at a selective advantage if the selective drug is present. That selective advantage will also result in the new drug resistance gene being added to preexisting multiple drug resistance plasmids.

Thus, taking Metformin will now select for multiple drug resistance that will be transferred to any pathogens. Common drugs indirectly select for and result in the construction of multiple antibiotic resistant super bugs.

Development of antibiotic super bugs has been blamed on abusive overuse of antibiotics in agriculture and medicine, but I think that the culprit is the natural antibiotic activity of common drugs. Drug use in general leads to super bugs. World use of pharmaceuticals needs to be reduced dramatically, e.g. a target of 1% of the current level! for antibiotics to remain useful.

Thanks for persisting in your questions.

Gretchen said...

What's your opinion of this comment?

"Recent animal studies have also found that metformin may actually play a role in shaping the gut microbiome. Metformin is a first-line drug for treating type 2 diabetes, but it is also sometimes prescribed for overweight and obese individuals seeking to lose weight. Although metformin has been used for decades, new research suggests it could hold the key to new treatments that target the intestinal flora. Preliminary studies reveal the positive effects of metformin – changes in the metabolic pathways of bacteria and growth of helpful bacteria, to name a few. While the exact details remain unknown, it’s fascinating to find that the medications we take can actually affect the microbes we host."

From http://www.diatribe.org/issues/64/what-were-reading

This suggests that yes, it affects bacteria, but it may select for helpful bacteria. I haven't read the article they cite as it's behind a paywall.

Dr. Art Ayers said...

Gretchen,
This is completely consistent with my perspectives of Metformin, which has beneficial effects on blood sugar levels by acting on gut flora. The action on gut flora is clearly selective and other studies show that it is an antibiotic. I just point out that the antibiotic activity of purified drugs always results in selection for corresponding resistance that ultimately leads to adding of that resistance to multiple antibiotic resistance plasmids. Subsequent use of Metformin or any of the antibiotic resistance genes on the plasmid, selects for all of the others simultaneously and the basis for super bugs is established.

It is easy to test if resistance genes for anti-diabetics, statins and NSAIDs already exist in hospitals on multiple antibiotic resistance plasmids.

Thanks for your comments.

Gretchen said...

I understand what you're saying. But I think we should try to reduce the massive use of regular antibiotics before we try to limit use of drugs that have beneficial effects on various diseases.

What we really need is new types of antibiotics that the bacteria can't build up defences against. If they ever figure out how to live in the presence of chlorine, we'll be in real trouble.

My grad school thesis was on enzymes that break down the polysaccharide coat on certain types of pneumococcus (now streptococcus pneumoniae). When the bacteria had no coats, they were not pathogenic. And you could, indeed, protect mice from pneumonia by injecting these enzymes.

But shortly after this was discovered (one of the discoverers was Avery, of Avery, McCloud, and McCarty fame), penicillin came around and the research on this was abandoned except for theoretical interest.

Of course, bacteria might develop ways of breaking down these enzymes. We need to find antibiotics of various different types to increase the probability that bacteria wouldn't be able to deal with at least some of them.

Dr. Art Ayers said...

Gretchen,
I agree that antibiotics are used excessively and the vast majority can be eliminated without major economic consequences except to pharmacy profits. Unfortunately, I think that the assumption that antibiotic use is the source of the rise of antibiotic resistance seems obvious, but is wrong.

Natural plant antibiotics, phytoalexins, have been isolated from plants, assessed for their pharmacological utility and repackaged as "beneficial drugs." They are just as active as antibiotics as their sister phytoalexins that are openly marketed as antibiotics and they represent the new classes of antibiotics that you would seek. However, all forms of antibiotics, including all natural phytoalexins, target bacterial gene products that are ever changing by rapid mutation.

Natural antibiotics that target bacterial cell wall components have been well studied and are readily produced as components of bacteriophages. They also readily produce resistant mutants. The same is true for phytoalexins and plant pathogens. Resistance is always produced.

Antimicrobial peptides (peptides with heparin binding domains), e.g. defensins, would be good candidates for antibiotics without well known resistance, and all of the possible sequences have been patented. Unfortunately, they are rather hard on gut flora.

Also note that most drugs act indirectly by using their inherent antibiotic activity to alter gut flora. It is the altered gut flora that provide the pharmaceutical benefit. That is what happens with the growth enhancing drugs, a.k.a. antibiotics, used in the cattle industry.

We use multiple antibiotics every time we eat veggies. That is the actual impact of phytochemical "antioxidants." These toxic phytochemicals continually alter our gut flora and are rapidly cleared, detoxified from our system.

I think the answer is to make people healthier rather than relying on drugs/antibiotics to fix the symptoms of disease. This means that the problem is predatory food and medical industries that make people sick and keep them sick. Prevention and cures are much cheaper than perpetual treatment.

Thanks for your comments. They help to clarify my points.

Raj said...
This comment has been removed by the author.
Gretchen said...

Making people healthier is a laudable goal. The problem is how.

Anna said...

Interesting blog! I am an MD and doing my PhD on effects of Metformin given to pregnant women. We have been giving pregnant women Metformin from first trimester until birth to see if it prevents pregnancy complications. It did not in our study. We are doing a follow up study, the oldest children are now 8. I am speculating how to best look for autoimmune disease in these children (and their mothers) resulting from Metformin use during pregnancy. Do you have any thoughts about that?

Natasha T. said...

Dear Dr. Ayers,

Thank you for the reply! I have ordered (!!!) a probiotic with Clostridium butyricum and will let you know how it goes.

Thanks to for this post about Metformin, just fascinating.

I am happy to tell you, I have half way through my small jar of my first home made fermented vegies. I took a workshop 3 weeks ago with the local . Organic green and red cabbage, ginger, garlic, hot green peppers and beets. I love the ginger part, don't care for the beets. I will attempt a bigger batch soon. :-) I have been eating lots of local kimchi, and have a "date" with my Korean friend's non-English speaking mom, to help make it the next time she does a batch.

I have learned so much on your blog, and I am reading and re-reading. My degree is arts, with only some science. Some things I will read and not understand until the very end, but the understanding is quite the reward!

I wanted to get your opinion on something else... My immune system reaction to potatoes includes - terribly painful and swollen joints (all, especially hip), crying, and anger. I have had to be careful with yams and sweet potatoes because I was having a similar problem. This past week, including today, I am having this reaction to plantain starch. :-( I think I triggered this by trying to eat potatoes last week after taking a series of SBO and BRM potato starch. Is this an immune system reaction as I suspect? It is so difficult to suddenly be in pain physically and not being able to control my emotions. The crying is sometimes accompanied by a sudden and extremely deep depression. It comes on one hour to exactly 24 hours after exposure, and lasts 24-36. When suffering, I wrack my brain for the things that upset me and I usually come up with a list of things my husband is deficient in.... I try to hold my tongue because I know my complaints against him are unfair... As you can imagine, I have avoided potatoes and starch religiously. I would love to be free of this....

Also, I have problems with scented laundry detergent. Yeah, really. It shuts down my brain. I can't think. I won't know what is wrong. I will just feel terrible. I used to have problems with all scents and all soaps. Now it is just scented laundry detergent - so I use unscented.

As you can imagine, none of this can be dealt with by my GP.

What do you think? Am I on the right track with all the changes I am making?

Thanks, Natasha

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blogger said...

Hi Anna, I was diagnosed with PCOS in my twenties and on metformin for seven years before having my two sons (had best diabetes for both). I did not take metformin during my first pregnancy and was hospitalized at 32,weeks with a partial placental abruption, low amniotic fluid, and breach presentation. I had him at 37 weeks via csection and he had many GI health issues and still does (,he is now six)., I went back on metformin during my second pregnancy and had no issues. My second son is much healthier. I now have sjogrens and possibly lupus and stopped metformin a couple of years ago due to B12,deficiency. Also my boys and I all have MTHFR defects and are positive for HLA B27.

Gretchen said...

Another recent article on metformin:

http://www.pnas.org/content/early/2014/05/29/1321776111

Anonymous said...

I am an MD....and had mother and grandfather die of pancreatic cancer and father developed diabetes type 2 and died of renal failure. I read in an MD Anderson study of diabetics treated with Metformin (5 years or so ago) drastically reduce their incidence of pancreatic CA. I decided then and there to take the plunge and go chronic Metformin. I think it was a decision with some merit.

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me said...

Fast for 18 hrs a day and you will drop it quickly. This will lower insulin levels. This will allow your body to release and not hang onto the fat. At the same time will be improving insulin sensitivity. THIS WORKS!! if you are having trouble doing the full 18 hrs do a min of 14-16. Good luck

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much, I just wanted to give him a try, he replied my mail and Needed
some Information about me, then I sent them to him, he prepared it
(CURE) and sent it to Airfreight Online Courier Service for delivery,
he gave my details to the Courier Office, they told me that 3-5 days I
will receive the package and i took the medicine as prescribed by him
and I went for check-up 1 week after finishing the medicine, I was
tested breast cancer negative, if you are breast cancer patient or any cancer patient at all. Do me
a favour for you to contact him and I will try my possible best to make
sure you get cured, when you contact him, make sure you tell him that
I referenced you.. contact him via: kokobiherbalremedycentre@gmail.com You can also message him on whatsapp +254746618873 and for more info message me @ pamela.drews77@gmail.com

Job Pedro said...

FINALLY FREE FROM HERPES VIRUSI thought my life had nothing to offer anymore because lifebecame meaningless to me because I had Herpes virus, thesymptoms became very severe and bold and made my familyrun from and abandoned me so they won't get infected. I gaveup everything, my hope, dreams,vision and job because thedoctor told me there's no cure. I consumed so many drugs butthey never cured me but hid the symptoms inside me makingit worse. I was doing some research online someday when Icame across testimonies of some people of how DR Ebhotacured them from Herpes, I never believed at first and thoughtit was a joke but later decided to contact him on the detailsprovided and when I messaged him we talked and he sent mehis herbal medicine and told me to go for a test after twoweeks. Within 7 days of medication the symptomsdisappeared and when I went for a test Lo and behold I wasNEGATIVE by the Doctor Who tested me earlier. Thank you DREbhota because I forever owe you my life and I'll keep ontelling the world about you. If you are going through samesituation worry no more and contact DR Ebhota viadrebhotasolution@gmail. com or WhatsApp him via +2348089535482.he also special on cureing 1. HIV/AIDS2. HERPES 3. CANCER 4.ALS 5. HEPATITIS B 6.DIABETES 7. HUMAN PAPILOMA VIRUS DISEASE(HPV)8. ALZHEIMER 9. LUPUS (Lupus Vulgaris or LupusErythematosus

Clara kat said...

I had my first outbreaks and I was tested back for both HSV-1 and 
HSV-2. Both my husband and I tested positive for HSV-1. Last year I found 
out my husband was cheating, so I decided to do a retest on all STDs 
including HSV-1 and HSV-2, only difference is that this time I went to a 
different clinic. Anyway I tested positive for HSV-1 which I knew I had but 
surprisingly HSV-2 as well, I was so upset and got divorced with my 
husband. 3 months ago a friend of mine recommended me to an African Herbal 
doctor DR.Edidia. I explained everything that I have been passing through 
all these years to him and he encouraged me that I will be cured 
completely!. I ordered for his herbal exploit/medicine and used it 
accordingly to his direction and within short period of using the herbal 
medicine I was cured completely from my HSV-1 and HSV-2. I'm so relieved to 
say that I've not had even one outbreak ever since again and I was also 
tested Negative by my doctor. I'm feeling so great! from within and I truly 
endorse this product, it really works. His herbal medicine is very active 
and effective, and other 
can of cure for HERPES, DIABETES, CANCER, HEPATITIS, HPV,HIV,COPD,KIDNEY FAILURE,PCOS and other diseases..... You can 
contact doctor edidia on email: dredidiaherbalhome@gmail.com and 
you can call/whatsapp him with +2349074505296 for your own cure too..    

visit his website https://dredidiaherbalhome.wixsite.com/dredidiaherbalhome
am clara kat here is my private email clarakat8@gmail.com

Angela Alex said...

Good day everyone, If getting HIV cure was that easy then why do a lot of people still suffer from HIV?. i was diagnosed of HIV back in 2013 and i was also told it has no cure, i have been leaving with it since then, but i kept praying and doing everything possible to get cured, so i never stopped doing research about finding a cure, i came across testimonies about people getting cured through herbal medication, and i have always believe in herbs and its medical properties, after doing so many research about it i found Dr. james was the one who cured them and i discovered he was a professional in herbal medication and he has also helped many people, i contacted him, we talked on phone and i confirmed he was genuine, i did all what he told me to do, i received the medicine he sent to me through courier delivery services. used it as he has prescribed, and glory be to God almighty GOD i am completely cured now, i went back to my doctor to confirm it. Do not be deceived THERE IS A CURE FOR HIV, doctors might tell you there is no cure but WITH HERBAL MEDICATION THERE IS A CURE and if you need to know or get cured from HIV or others disease such as Herpes virus, yeast infections, Parkinson's disease,Schizophrenia,Cancer,Scoliosis,Bladder Cancer,Colorectal Cancer,Breast Cancer,Kidney Cancer,Leukemia,Lung Cancer,Skin Cancer,Uterine Cancer,Prostate Cancer,Fibromyalgia,a
Syndrome Fibrodysplasia ,Epilepsy Dupuytren's disease, Diabetes ,Coeliac disease, Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Sclerosis,Alzheimer's disease,Adrenocortical carcinoma.Asthma,Allergic diseases.Hiv_ Aids,Herpes,Inflammatory bowel disease ,Copd,Diabetes.    contact Dr. James through Email: drjamesherbalmix@gmail.com And You can call/WhatsApp dr James on +2348152855846    

marry lawson said...

HOW I WAS CURE FROM HERPES WITHIN  14DAYS WITH THE HELP OF DR ZUBBY HERBAL MEDICINE CONTACT DR ZUBBY HIS website 
 https://drzubbyherbalcure.weebly.com/
I am so Happy to be writing this article in here, i am here to explore blogs from about the wonderful and most safe cure for HERPES SIMPLEX VIRUS I was positive to the Virus called HERPES and i lost hope completely because i was rejected even by my closet friends. i searched online to know and inquire about cure for HERPES and i saw testimony about DR ZUBBY online on how he cured so many persons from Herpes Disease so i decided to contact the great herbalist because i know that nature has the power to heal everything. i contacted him to  just like me! and if you need his help WhatsApp him +2348070673249 He also have the herbs to cure difference cure  for any sickness 
(1) HERPES,
(2) HIV
(3) CANCER
(4) DIABETES,
(5) HIV&AIDS,
(6) URINARY TRACT INFECTION,
(7) HEPATITIS B,
(8) BARENESS/INFERTILITY
(9) DIARRHEA
(10) ASTHMA...

 kindly email DR ZUBBY for your own cure if you have any disease listed and his email (dr.zubbysolutionhome@gmail.com) His WhatsApp no +2348070673249
 his fb page https://www.facebook.com/dr_zubby04-108328840861468

https://www.facebook.com/Drzubby-herbla-home-112207317016092  

Anita Lawson said...

It’s obvious some patients with herpes are being enslaved to the antiviral and other supplementary Orthodox medicine just to help suppress the virus and not a cure. I have been with the virus since 2015 until I was introduced by a blogger who also narrated her story online on how she was cured of Genital Herpes after using Dr Sikies Herbal Medicine. This is a year and 2 weeks since I was delivered from genital Herpes. All thanks to God for using this Great herbalist to heal me. I have promised to keep telling good things about Dr Sikies. Please feel free to share Your problems with him and don’t forget to tell him I did refer you to Him. Thanks. Write him on mail Drsikies@gmail.com He deals with Alzheimer virus, Cancer, HIV, Herpes, Genital, warts, ALS, BV, UTI, Virginal infection, Genital, Wart, HPV, Hepatitis A/B, Good luck, HSV, Pregnancy, Ex back.  

here is his website:https://drsikiesherbalcure.weebly.com 

you can reach me via mail:anitalawson515@gmail.com

marry judith said...

FINALLY FREE FROM CANCER DISEASE.
what a miracle i never believe there is cure because my doctor tested me cancer positive and she told me there is no cure, i’m very happy today that i’m having a free life without this CANCER diseases, i can remember some months ago when i was crying all through the night and day that i can’t get cured from this CANCER, i found this herbal man called Dr adazal on internet when i was doing research on cure for shingle i contacted him to found out if i can get help from this cancer diseases, i was so surprise when he told me that he have the herbs cure to it and he sent me the herbal in less down 5 days i was so happy when i get someone giving me hope that he can cured me i took the herbal for just 2 weeks, when i went for test after taking the herbal i found out that i am cured i was so happy and surprise, i want to use this opportunity to inform you that there is cured to cancer diseases you can also contact him for his help as soon as possible so that you can get rid of this cancer once and for all you can reach him through this email: dr.adazalherbalcure@gmail.com or whatsApp him on +2348073688335 You can also contact him on any disease and virus in this he all have the herbal cure to it.
1 HIV/AIDS
2 HERPES
3 CANCER
4 ALS
5 HEPATITIS
6 DIABETES
7 LOVE SPELL
8 INFECTIONS
9 HIGN BLOOD PRESSURE,.....
THANKS TO DR adazal FOE THE GOOD WORK IN LIFE YOU ARE TRULY A BLESS.  you can visti his fb page https://www.facebook.com/Dradazalherbalcure-113851246922332/  And Adazal   Website  https://dr-adazal-herbal-cure.jimdosite.com/

Clara david said...

WHAT A GREAT MIRACLE THAT I HAVE EVER SEE IN MY LIFE. My names are Clara David I’m a citizen of USA, My younger sister was sicking of breast cancer and her name is Sandra David I and my family have taking her to all kind of hospital in USA still yet no good result. I decided to search for cancer cure so that was how I found a lady called Peter Lizzy. She was testifying  to the world about the goodness of a herbal man who has the roots and herbs to cure all kinds of disease and the herbal man's email was there. So I decided to contact the herbal man @herbalist_sakura for my younger sister's help to cure her breast cancer. I contacted him and told him my problem he told me that I should not worry that my sister cancer will be cure, he told me that there is a medicine that he is going to give me that I will cook it and give it to my sister to drink for one week, so I ask how can I receive the cure that I am in USA, he told me That I will pay for the delivery service. The courier service can transport it to me so he told me the amount I will pay, so my dad paid for the delivery fee. two days later I receive the cure from the courier service so I used it as the herbal man instructed me to, before the week complete my sister cancer was healed and it was like a dream to me not knowing that it was physical I and my family were very happy about the miracle of Doctor so my dad wanted to pay him 5 million us dollars the herbal man did not accept the offer from my dad, but I don't know why he didn't accept the offer, he only say that I should tell the world about him and his miracle he perform so am now here to tell the world about him if you or your relative is having any kind of disease that you can't get from the hospital please contact dr.sakuraspellalter@gmail.com or whats app him +2348110114739  you can follow him up on Instagram @herbalist_sakura for the cure, he will help you out with the problem. And if you need more information about the doctor you can mail me davidclara223@gmail.com 

Richard William said...

Am Richard, I am here to testify about a great herbalist  man who cured my wife of breast cancer. His name is Dr Imoloa. My wife went through this pain for 3 years, i almost spent all i had, until i saw some testimonies online on how Dr. Imoloa cure them from their diseases, immediately i contacted him through. then he told me the necessary things to do before he will send  the herbal medicine. Wish he did through DHL courier service, And he instructed us on how to apply or drink the medicine for good two weeks. and to greatest surprise before the upper third week my wife was relief from all the pains, Believe me, that was how my wife was cured from breast cancer by this great man. He also have powerful herbal medicine to cure diseases like: Alzheimer's disease, parkinson's disease, vaginal cancer, epilepsy Anxiety Disorders, Autoimmune Disease, Back Pain, Back Sprain, Bipolar Disorder, Brain Tumor, Malignant, Bruxism, Bulimia, Cervical Disc Disease, Cardiovascular Disease, Neoplasms , chronic respiratory disease, mental and behavioral disorder, Cystic Fibrosis, Hypertension, Diabetes, Asthma, Autoimmune inflammatory media arthritis ed. chronic kidney disease, inflammatory joint disease, impotence, alcohol spectrum feta, dysthymic disorder, eczema, tuberculosis, chronic fatigue syndrome, constipation, inflammatory bowel disease, lupus disease, mouth ulcer, mouth cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, HIV / AIDS, Huntington's disease, back acne, chronic kidney failure, addison's disease, chronic pain, Crohn's pain, cystic fibrosis, fibromyalgia, inflammatory Bowel disease, fungal nail disease, Lyme disease, Celia disease, Lymphoma, Major depression, Malignant melanoma, Mania, Melorheostosis, Meniere's disease, Mucopolysaccharidosis, Multiple sclerosis, Muscular dystrophy, Rheumatoid arthritis. You can reach him Email Via drimolaherbalmademedicine@gmail.com / whatsapp +2347081986098    Website/ www.drimolaherbalmademedicine.wordpress.com

Meagan Flugence said...

Thank God for using Dr Ojamo to get me cured from Herpes virus
The disease appeared at the age of 38, with no hope of a cure from the hospitals i have went to, I thought my life have come to an end, until a friend of mine told me about Dr, Ojamo who treats all Kinds of
diseases including Herpes, I contacted him via his email: dr.ojamoherbalhome@gmail.com and purchased the Herpes drug which is in a form of liquid after preparation, I received the medicine
through airwingexpressdelivery and immediately commenced usage as prescribed, i used the medicine within 3weeks that i was instructed and to my greatest surprise my result became negative I am Herpes free, and I won't stop rejoicing and giving thanks to God for using Dr ojamo to cure me, you can contact him for your cure or any kinds of drugs, contact his Whatsapp number +2349077406037 or email dr.ojamoherbalhome@gmail.com

Meagan Flugence said...

Thank God for using Dr Ojamo to get me cured from Herpes virus
The disease appeared at the age of 38, with no hope of a cure from the hospitals i have went to, I thought my life have come to an end, until a friend of mine told me about Dr, Ojamo who treats all Kinds of
diseases including Herpes, I contacted him via his email: dr.ojamoherbalhome@gmail.com and purchased the Herpes drug which is in a form of liquid after preparation, I received the medicine
through airwingexpressdelivery and immediately commenced usage as prescribed, i used the medicine within 3weeks that i was instructed and to my greatest surprise my result became negative I am Herpes free, and I won't stop rejoicing and giving thanks to God for using Dr ojamo to cure me, you can contact him for your cure or any kinds of drugs, contact his Whatsapp number +2349077406037 or email dr.ojamoherbalhome@gmail.com

jane scott said...

I GOT CURED FROM HERPES VIRUS I was diagnosed of HERPES virus and i have tried all I can to get cured but all to no avail,,until I saw a post in a health forum about a herbalist man who prepare herbal medications to cure all kind of diseases including #HERPES virus,at first I doubted if it was real but decided to give it a try,when I contacted this herbalist via his email and he prepared a #HERPES herbal cure and sent it to me via DHL delivery company service, when I received this herbal medicine, he gave me step by direction on how to apply it,after applying the way I was instructed,I was totally cured of this deadly disease called HERPES, all thanks to Dr OGODO Email this great herbal doctor via his email Ogodoherbalhomesolution@gmail.com
You can also WhatsApp him on +2349044680467
HE CAN ALSO CURE SICKNESS LIKE
{1}HIV/AIDS
{2}DIABETES
{3}EPILEPSY
{4} BLOOD CANCER
{5} HPV
{6} ALS
{7} HEPATITIS
{8}LOVE SPELL
{9} SICKLE AND ANEMIA
Only DR OGODO Can Help You I Love You Father.

Jessica Morgan said...

Good news this is to everyone out there with different health challenges, as I know there are still a lot of people suffering from different health issues and are therefore looking for solutions. I bring you Good news. There is a man called Dr ehiaguna a herbal practitioner who helped cure me from HSV (2), i had suffered from this diseases for the past 5 years and i have spent so much money trying to survive from it. I got my healing by taking the herbal medicine Dr ehiaguna sent to me to drink for about 14 days . 3 days after completion of the dosage, I went for a medical checkup and I was tested free from HSV. all thanks to God for leading me to Dr ehiaguna who was able to cure me completely from this deadly diseases, I’m sharing this so that other people can know of this great healer called Dr ehiaguna because I got to know him through elizabeth who he cured from HIV. I was made to understand that he can cure several other deadly diseases and infections. Don’t die in ignorance or silent and don’t let that illness take your life. Contact Dr ehiaguna through his email  drehiaguna@gmail.com You can also whatsapp/call him on:+2348073908953 . Visit his website  https://effectiveherbalcurehome.blogspot.com/   He cure all forms of disease {1}HIV/AIDS {2}DIABETES {3}EPILEPSY {4} BLOOD CANCER {5} HPV {6} BRAIN TUMOR {7} HEPATITIS {8}COPD{9} SICKLE AND ANAEMIA.etc Be kind enough to share as you received.  

fredrik palm said...

I’m recommending Dr Godday to everyone who have herpes virus to get the cure from him. I was diagnose of genital herpes in 2015 and i have been searching and asking questions to see if i could get something to cure the disease because i did not believe what the doctors say that no cure is found yet. I came across a comment on Youtube and the person testify how she was cured from herpes and hpv after using Dr Godday herbal medicine. I quickly contact Dr email and explain my problem to him and he prepare the herbs and send it to me through courier and gave me instructions on how to use it and tell me to go for checkup after usage which i did after two weeks of taken the herbal medicine and my result was NEGATIVE. I waited another month and retested the result was still NEGATIVE and my doctor told me that am completely free from herpes. Am so happy and grateful to Dr Godday for what he has done for me and i will continue to share this for people out there to know that there is cure for herpes. You can contact Dr Godday on email and WhatsApp to get the cure from him. Email:goddayspiritualhome@gmail.com Or Call/What’s-app +1{919}4956404

Success James said...



I am so Happy to be writing this article in here, i am here to explore blogs forum about the wonderful and most safe cure for HERPES SIMPLEX VIRUS.I was positive to the Virus called HERPES and i lost hope completely because i was rejected even by my closet friends. i searched online to know and inquire about cure for HERPES and i saw testimony about DR Ebhota online on how he cured so many persons from Herpes Disease so i decided to contact the great herbalist because i know that nature has the power to heal everything. i contacted him to know how he can help me and he told me never to worry that he will help me with the natural herbs from God! after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via FEDEX or DHL and it got to me after 4 days! i used the medicine as he instructed me (MORNING and EVENING) and i was cured! its really like a dream but i'm so happy! that's the reason i decided to also add more comment of Him so that more people can be saved just like me! and if you need his help,contact his Email: (drebhotasoltion@gmail.com) You can contact him on WhatsApp +2348089535482 He also have the herb to cure difference cure for any sickness (1) HERPES,
(2) DIABETES,
(3) HIV&AIDS,
(4) URINARY TRACT INFECTION,
(5) HEPATITIS B,
(6) IMPOTENCE,
(7) BARENESS/INFERTILITY
(8) DIARRHEA
(9) ASTHMA..

sarah rita said...

Hello everyone i was diagnose of herpes simplex virus for about 8months ,I’ve lost all hope and my doctor said there is no possible cure and I have been taken antiviral to sustain myself I have had several out break from the time I was diagnosed till I got to know about Dr.obudu through a friend who he cured of Herpes . I contacted him and he sent me his herbal remedy which I took as he directed me to do for some days and I went to the hospital after consuming his Herbal medicine and I was confirmed Herpes Negative after 8 months of pains and depression , it was indeed a miracle, Dr.Obudu is a great man, I have heard so much about how he has help lot of people, He also cure ALS, HEPATITIS B, CANCER, HERPES, DIABETES and lots more. if you have any issue you can contact him for help add him on whatsapp +2349023428871. or via email:Email drobuduherbalhome@gmail.com or vist his website https://drobuduherbalhome.wixsite.com/welcometoobuduherbal or visit his facebook page https://www.facebook.com/DR-OBUDU-101779795066025/

Frank Roland said...

I have be living with Oral herpes for over 4 years now and it has be a big problem for me.I have been looking for solution because i can't leave with it, One day i came across a woman testimony on a forum saying she got cured of her Herpes with the help of Dr Ojamo an herbal doctor from african with herbal medicine. At first i did not believe because i was not sure herbs can really take this virus away,but i have no choice than to give it a try and contacted him with his emails, i explain my problems,.. then he told me not to worry that he will prepare the a cure with herbal mixture and send it to me, i got the medicine after 4days delivery and i use as instrusted. After 21days when the herb got almost finish i went to a medical doctor, i did a test and discover that the virus was gone, and my test result were HSV 1%2 negative,i was so surprise and happy! then i wrote dr Ojamo and thank him for getting me cured from herpes. I advice you to contact this great herbal doctor Ojamo as he have cure for different kinds of diseases.i decided to share this testimony to let others who also suffer from herpes know about this and give HOPE to others, you can reach him via Email dr.ojamoherbalhome@gmail.com WhatsAPP number +2349077406037


You can check on his website for more info https://drojamoherbalhome.wixsite.com/welcometodrojamoherb

sarah rita said...

Hello everyone i was diagnose of herpes simplex virus for about 8months ,I’ve lost all hope and my doctor said there is no possible cure and I have been taken antiviral to sustain myself I have had several out break from the time I was diagnosed till I got to know about Dr.obudu through a friend who he cured of Herpes . I contacted him and he sent me his herbal remedy which I took as he directed me to do for some days and I went to the hospital after consuming his Herbal medicine and I was confirmed Herpes Negative after 8 months of pains and depression , it was indeed a miracle, Dr.Obudu is a great man, I have heard so much about how he has help lot of people, He also cure ALS, HEPATITIS B, CANCER, HERPES, DIABETES and lots more. if you have any issue you can contact him for help add him on whatsapp +2349023428871. or via email:Email drobuduherbalhome@gmail.com or vist his website https://drobuduherbalhome.wixsite.com/welcometoobuduherbal or visit his facebook page https://www.facebook.com/DR-OBUDU-101779795066025/

Ava Brandon said...

Finally I am free from herpes virus, with the help of Dr.Omola pure herbs, This Virus appeared at the age of 29, with no hope of a cure from the hospitals i have went to, I thought my life have come to an end, until a Facebook friend of mine told me about Dr. Omola who treats all Kinds of diseases including Herpes, I contacted him via his email: dr.omolaherbalhome@gmail.com, I explain everything to him so he ask for my home address, after telling me the cost of the herbal medicine so we agree at a particular price, he prepare the herbs and make delivery to me via FedEx delivery service they deliver the herbs to my door step, I drink the herbs as him instructed, I went for test in 3 different hospital and it was negative, today I'm free from herpes virus.
You should try Dr.omola herbs I'm not the first person to be cured with his herbs there are different testimony about this herbal doctor, your case can not be different, here is his WhatsApp No +2348118116254 email: dr.omolaherbalhome@gmail.com.

cynthia williamas said...

HOW I GOT CURED FROM HPV WARTS Greetings to the general public, i want to tell about how i was cured of HPV disease by a Doctor called DR MOMOH i was browsing through the Internet searching for remedy on HPV and i saw comment of people talking about how DR MOMOH cured them. I Was scared because i never believed in the Internet but i was convince to give him a try because i having no hope of been cured of HPV so i decided to contact him with his email that was listed on the comment when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without problem, my HPV result came out negative. I pray for you God will give you everlasting life, you shall not die before your time for being a sincere and great man. Am so happy, you can also contact him if you have any problem Email: dr.momoh9@gmail.com website on: https://drmomohherbaltreatment.wordpress.com or whatsApp him on this number +2347083724098 1. LOVE SPELL 2. ALS CURE 3. HEPATITIS B 4. HIV/AIDS CURE 5. HERPES CURE 6 SPIRITUAL HEALERS

Julia Franklin said...

So is possible that HIV Disease can be cured because I have been scammed so many times not until I came across this great man herbalist Dr Akhigbe who helped me at first I never believe all this comment and post about him and I was very sick because I have been infected with HIV/AIDS for the past two year,just last two months I keep reading the testimony about this man named Dr Akhigbe they said that the man is so powerful he have cured different type of diseases, I keep monitoring his post of some people about this man and I found out that he was real so I decided to give him a trial I contacted him for help and he said he was going to help me get my cure that all I needed to do was to send him money to prepare the medication after which it will be sent to me via DHL courier delivery services which I did to my greatest surprise the medication was sent to me he gave me instructions to follow on how to drink it that after  three weeks I should go for check up,after taking the medicine and follow his instruction after three weeks I went back to the hospital for another test, at first I was shocked when the doctor told me that I was  negative I ask the doctor to check again and the result was still the same negative that was how I free from  HIV VIRUS at of the shock I decided to come and share my own testimony with you for those who think there is no cure for HIV VIRUS the cure as finally come'  out stop doubting and contact Dr Akhigbe via email drrealakhigbe@gmail.com he will help you out you can also whats App him via +2348025012866 he is also perfect in curing DIABETICS,HERPES,HIV/AIDS, ;ALS,  CANCER , MALARIA , BACTERIA DIARRHEA, MENINGITIS,HEPATITIS A AND B,ASTHMA, HEART DISEASE, CHRONIC DISEASE. NAUSEA VOMITING OR DIARRHEA, KIDNEY DISEASE,, IMMUNE SYSTEM BOOSTING.  SCHIZOPHRENIA, LUPUS,EXTERNAL INFECTION, COMMON COLD, JOINT PAIN, OSTEOPOROSIS, RABIES RHEUMATISM, THYROID, GALLSTONE, TETANUS, COLD & FLU, DENGUE, HUNTINGTON'S DISEASE, PROSTATE, CIRRHOSIS, DENGUE FEVER, SCABIES, EPILEPSY,STROKE,TUBERCULOSIS ,STOMACH DISEASE. ECZEMA, SMALLPOX,  PROGERIA, EATING DISORDER, LOWER RESPIRATORY INFECTION. etc . Believe me that deadly disease is no longer a deadly sentence because Dr. Akhigbe has the cure.the godfather of herbal root.email: drrealakhigbe@gmail.com         whatsapp number.  +2348025012866 website: https://drrealakhigbe.weebly.com  

sarah rita said...

I want to thank Dr OBUDU for the help he has rendered to me by getting Ridof my (HSV-2). I was Diagnosed in July 2018 but after the Usage of Dr OBUDU Herbal Medicine, I was cured from (HSV-2) and the virus was completely gonefrom my body. The Symptoms of the (HSV-2) Virus is completely Gone.. Soanyone who is having the virus should contact Dr OBUDU to give you theherbal medicine to cure yourself. HERPES, You can contact dr OBUDU on Whatsapp +2349023428871 or email: drobuduherbalhome@gmail.com. Also visit he’s website https://drobuduherbalhome.wixsite.com/welcometoobuduherbal He cures all this  illness,. 1 cancer cure2 diabetes cure3 ringing ear4 herpes cure5 warts cure6 HPV cure7 Hiv8 get your ex back9 pregnancy herbal medicine10 prostate enlargement11 Hepatitis B….

Clara david said...

WHAT A GREAT MIRACLE THAT I HAVE EVER SEE IN MY LIFE. My names are Clara David I’m a citizen of USA, My younger sister was sicking of breast cancer and her name is Sandra David I and my family have taking her to all kind of hospital in USA still yet no good result. I decided to search for cancer cure so that was how I found a lady called Peter Lizzy. She was testifying  to the world about the goodness of a herbal man who has the roots and herbs to cure all kinds of disease and the herbal man's email was there. So I decided to contact the herbal man @herbalist_sakura for my younger sister's help to cure her breast cancer. I contacted him and told him my problem he told me that I should not worry that my sister cancer will be cure, he told me that there is a medicine that he is going to give me that I will cook it and give it to my sister to drink for one week, so I ask how can I receive the cure that I am in USA, he told me That I will pay for the delivery service. The courier service can transport it to me so he told me the amount I will pay, so my dad paid for the delivery fee. two days later I receive the cure from the courier service so I used it as the herbal man instructed me to, before the week complete my sister cancer was healed and it was like a dream to me not knowing that it was physical I and my family were very happy about the miracle of Doctor so my dad wanted to pay him 5 million us dollars the herbal man did not accept the offer from my dad, but I don't know why he didn't accept the offer, he only say that I should tell the world about him and his miracle he perform so am now here to tell the world about him if you or your relative is having any kind of disease that you can't get from the hospital please contact dr.sakuraspellalter@gmail.com or WhatsApp him +2348110114739  you can follow him up on Instagram @herbalist_sakura visit his website     https://drsakurahealthclinic.wixsite.com/website https://sites.google.com/view/herbalistsakura                               https://drsakuraspellcentre.blogspot.com/                 https://drsakuraspellcentre.wordpress.com/         for the cure, he will help you out with the problem. And if you need more information about the doctor you can mail me    davidclara223@gmail.com

clara said...

Dr Oduku herpes treatment is one of the most effective home remedies for herpes which has the ability to kill the herpes virus permanently. I found out I had herpes 4 years ago. My first outbreak was definitely the worst thing I ever experienced. The bumps and blisters were swollen and red. I had a doctor give me Valtrex but I take the generic. I had to take the Valtrex 1 gram a day for about a week and I had another doctor prescribe me Acyclovir but that gave me the worst headaches ever, so I stopped taking it.after 2 year all that prove abortive the herpes was still there,Since I was first diagnosed I have about 2 outbreaks a month. I have been able to cope with this by having supportive family and friends who look out for me,though it wasnt easy for me, one day i read a post by someone testifying about Dr  Oduku that she was cured totally using his herbal product, i decided to gave it a try, I contacted him as instructed in the testimony. i made request for the herbal medicine, he actually did send it to me and gave me the instruction on how i will use it,The good news is this, i went to the hospital after the medication for test as instructed by Dr Oduku, i was tested negative, i was suprised finding out that am now herpes virus negative against my former result which was positive, Am happy to let the whole world know that today am free from this herpes disease,no more outbreak, no more cold sores, excruciating pains, i will advice anyone reading this message  and needed a cure for herpes as well should please contact this Great Dr Oduku on drodukuherbalhealingcentre@gmail.com or WhatsApp +2348124765093
Visit his website: https://dr-oduku-herbal-healing-centre.jimdosite.com
https://drodukuherbscure.blogspot.com/
Dr Oduku is the best herbal doctor.

Sandy Soto said...

Hi, is a true life experience is not designed to convince you its a personal health experience, sometimes medical doctors take a different approach about herpes treatment. i has been stocked in bondage with herpes for two years and four months i has tried different means to eliminate this sickness because it surely has distract me even with the world, and i was told there is no cure, but only medicine for treatment all the possible ways i has tried was treatment, two months back i did some herpes research and i found amazing testimonies concerning natural herbal cure, and i go for it through the email address from the post just to give a try of herbal treatment, and i found it grate without delay i got cured with natural treatment from doc Twaha herbal cure his cure are powerful and shows out excellent result. and i think everyone suffering with herpes and others symptoms should also know about this cure from, drlregbeyen10000@gmail.com or WhatsApp him +2349038518881 thank you

Tanisha Sharell said...

Living with herpes virus was the worst situation I've ever been in due to work and tending to my family needs but finally tested negative after using the herbal medicine I ordered from him. His Email drodiagbesolutionhome@gmail. com

Floritino Jani Renaur said...

I was in trouble when my doctor told me that I have been diagnosed with Colon Cancer Disease… I thought about my children, I know my children will face a serious problem when I'm gone, I lost hope and I wept all day, but one day I was surfing the internet, I found a testimony of someone that was cured of CANCER Disease by Dr Odudu. I collected his contact email. I mailed him and he guided me. I asked him for solutions and he started the remedies for my health. Thank Allah, now everything is fine, I'm cured by Dr.ODUDU herbal medicine, I'm very thankful to Dr Odudu. And now, I'm happy with my loved ones again. You can also email him on dr.oduduherbalhome@gmail.com phone number (whatsapp) or call +2348101571054. you can easily reach him If you have a similar problem. https://www.facebook.com/DR.ODUDU

Rachelle Henley said...

I am so Happy to be writing this review here, i am here to explore blogs forum about the wonderful and most safe cure for HERPES SIMPLEX VIRUS. I was tested positive to the deadly Virus, HERPES and i lost hope completely because i was rejected even by my closet friends. i searched online to know and inquire about cure for HERPES and i saw Dr Ojamo testimony online on how he has cured so many persons from Herpes Disease so i decided to contact this great herbalist because i know that nature has the power to heal everything. i contacted him to know how he can help me and he told me never to worry that he will help me with the natural herbs from God! after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via FED-EX and it got to me after 4 days! i used the medicine as he instructed me (MORNING and EVENING) and i was cured! its really like a dream but i'm so happy! that i was cured. that's the reason i decided to also add more comment of Him so that more people can be saved just like me and if you need his help contact his Email: dr.ojamoherbalhome@gmail.com you can also contact him on mobile number and via whats app +2349077406037


You can check on his website for more info https://drojamoherbalhome.wixsite.com/welcometodrojamoherb

Clara david said...

WHAT A GREAT MIRACLE THAT I HAVE EVER SEE IN MY LIFE. My names are Clara David I’m a citizen of USA, My younger sister was sicking of breast cancer and her name is Sandra David I and my family have taking her to all kind of hospital in USA still yet no good result. I decided to search for cancer cure so that was how I found a lady called Peter Lizzy. She was testifying  to the world about the goodness of a herbal man who has the roots and herbs to cure all kinds of disease and the herbal man's email was there. So I decided to contact the herbal man @herbalist_dr_sakura for my younger sister's help to cure her breast cancer. I contacted him and told him my problem he told me that I should not worry that my sister cancer will be cure, he told me that there is a medicine that he is going to give me that I will cook it and give it to my sister to drink for one week, so I ask how can I receive the cure that I am in USA, he told me That I will pay for the delivery service. The courier service can transport it to me so he told me the amount I will pay, so my dad paid for the delivery fee. two days later I receive the cure from the courier service so I used it as the herbal man instructed me to, before the week complete my sister cancer was healed and it was like a dream to me not knowing that it was physical I and my family were very happy about the miracle of Doctor so my dad wanted to pay him 5 million us dollars the herbal man did not accept the offer from my dad, but I don't know why he didn't accept the offer, he only say that I should tell the world about him and his miracle he perform so am now here to tell the world about him if you or your relative is having any kind of disease that you can't get from the hospital please contact dr.sakuraspellalter@gmail.com or WhatsApp him +2348110114739  you can follow him up on Instagram @herbalist_dr_sakura visit his website     https://drsakurahealthclinic.wixsite.com/website https://sites.google.com/view/herbalistsakura                               https://drsakuraspellcentre.blogspot.com/                 https://drsakuraspellcentre.wordpress.com/         for the cure, he will help you out with the problem. And if you need more information about the doctor you can mail me    davidclara223@gmail.com

alexandra alana said...

I got Diagnosed with Herpes, I have be dealing with Herpes for the past 4 years. On till I got review online about natural cure people testifies how DR.OBUDU cure them with his herbal treatment. And I order the treatment, after taking it for 21 days I totally got cured with DR. OBUDU treatment. I'm recommending you diagnosis with herpes should get this treatment and be cured of it you can contact his email address via; drobuduherbalhome@gmail.com or you can also call or whatsApp +2349023428871 Website: https://drobuduherbalhome.wixsite.com/welcometoobuduherbal
also cure the following virus and many more... 1} Cancer 2} Diabetes 3} Hepatitis 4} fibroid 5} herpes 6} Lupus

Tyrone David said...

This is so amazing and so much reminds me of my Dad’s battle with Parkinson's disease and stroke. I think the biggest trauma was much on the family. You know, watching your agile father became so fragile and a shadow of himself. He became dependent on grand kids to move him around and feed too. It was really heartbreaking for everyone! But each time I remember the story, I become so thankful that we were opportune to learn about Dr. OVIE through the internet and used his herbal medicine which helped my Dad. Though I read a lot of negative things about herbs for Parkinson's disease and attendant effects of stroke treatment, I can tell you that the right herbal medicine is still out there! We found ours through Ovie. My Dad was 75 when he had an attack with Parkinson's disease which led to stroke. We used all recommended over-the-counter medicines for him for a period of 3 years, yet, there was no cure and to think those drugs had very bad side effects on him became our new challenge. When we switched to homeopathic treatment, he got a little better. Our breakthrough was through Dr. OVIE Herbal Medicine. That medicine was a miracle our family will never forget. In 2 months of use, his body was totally revived! His stroke vanished while Parkinson's disease was completely cured. Dad turned 87 august 01 th and is still very strong. Occasionally tending his garden with grandchildren. I will say, give Ovie a try, you never know your breakthrough from Parkinson's disease and stroke is very close to you an email away. ontact Dr Ovie via email> ovie.miraclemedicine1@gmail.com or contact Dr Ovie on yahoo email> ovie.miraclemedicine1@yahoo.com contact Dr.Ovie on his website now https://oviemiraclemedicin.wixsite.com/mysite Call or WhatsApp Dr on +2349056393169 aaDr Ovie is also specialize in curing the following below,*PARKINSON DISEASE
*CANCER
*STROKE
*INFERTILITY
*HEART DISEASE
*HIV
*COLD SORES
*DIABETES*LUPUS DISEASE*HPV*HSV1&2.

leonard shirin said...


I WANT TO USE THIS OPPORTUNITY TO SAY A VERY BIG THANK YOU TO DR Ogberaese, My name is Leonard Shirin i am so happy to share this testimony on how Dr.Ogberaese healed me from genital herpes. i was detected with genital herpes around 10th may
2019, and ever since that day i have been looking for a way to end this virus from my body, but the more i try, the more i was told there was no solution. Few months ago i saw a testimony of some people on how Dr Ogberaese cure them from HERPES VIRUS, i also heard about it on media when a young lady also gave her testimony saying Dr Ogberaese cured her oral herpes. I was left with no other hope than to contact Dr Ogberaese and give him a try. I contacted him and told him what i was going through. He said he could heal me, that he is going to send me a herbal medicine and He sent the medicine as he promised. I took this herbal medicine for 1 week and it was obvious that his medicine was for real, because the herpes started clearing from my body. Later at the 2 week, i went for medical check up and i was surprised when my doctor told me he found no trace of the virus in me again. At first when he told me, i was so shock and still did not believed until he gave me my test result. to make my story short i am now free from herpes, after many months of sorrow and my sickness is gone, i thank God for leading me to this man, and i want to also lead you to him if you have any illness like HIV, HPV, hepatitis B, asthma, cancer, Diabetes, COLD SCORE,TOOTH ACHE FIBROID and AUTISM. You can email him on drogberaese54@gmail.com or whats-app him on +2348073818653. visit him on his website: https://dr-ogberaese-herbal-home.jimdosite.com

Pius Richard said...

How can I explain this to the world that there is a man who can cure HERPES, I was diagnosed for the past 5 mouth I have being into HERPES since 5 mouth, so I decide to look for help in the internet then I found a post write about this great man called DR. Ehimare , people say good thing about him that this man have cured, a lot of people in the internet, him has power's to cure HSV1 AND HSV2 I don’t believe that there is a cure for Herpes Simplex Virus because though there is no cure for herpes that what I have in mind HERPES had no cure well , my HERPES is negative through the using of herbal cured of DR. Ehimare , I contacted this man for help because of what i see in the internet. if you need his cured just add him now on Hangouts Drehimare3@gmail.com , thank you DR.Ehimare i will never stop  shearing you testimony DR. Ehimare him Can as well CURE THE FOLLOWING DISEASE:-1, HIV/AIDS, 2, Diseases of the hear 3, Malignant tumors 4. Cardiovascular diseases 5. Diabetes mellifluous 6.Influenza and pneumonia 7.Alzheimer's disease 8. hsv1 - hsv2. If you need LOVE SPELL. E.T.C contact him Drehimare3@gmail.com or you whatsapp him on + 1 (267) 691-1087

Kimberly Thomas said...

Myles was a 20 year-old man who was brought to the emergency room by the campus police of the college from which he had been suspended several months ago. A professor had called and reported that Myles had walked into his classroom, accused him of taking his tuition money and refused to leave. I was as shocked as a father, Although Myles had much academic success as a teenager, his behavior had become increasingly odd during the past year. He quit seeing his friends and no longer seemed to care about his appearance or social pursuits. He began wearing the same clothes each day and seldom bathed. He lived with several family members but rarely spoke to any of them. When he did talk to them, he said he had found clues that his college was just a front for an organized crime operation. He had been suspended from college because of missing many classes. His sister said that she had often seen him mumbling quietly to himself and at times he seemed to be talking to people who were not there. He would emerge from his room and ask his family to be quiet even when they were not making any noise.I could not stand the shame of my son illness so I decide to consult some of my africa friends at work , and then Tasha introduced me to Dr. Itua who uses her herbal medicines to cure her Hiv and Prostate Cancer after the herbal medicine consumption. I place an order for my son and he hands it to my post office, then I pick it up and use it for three weeks. My son 's treatment was done and he is now doing good and behaving normally like a human being is supposed to. is completely healed. I tell you honestly that this man is a great man, I trust him Herbal medicine so much that I share this to show my gratitude and also to let sick people know that there is hope with Dr. Itua. Herbal Center.Dr Itua Contact Email.drituaherbalcenter@gmail.com/Whatsapp+2348149277967. He cures, Herpes, Prostate, Breast Cancer, Brain Cancer, CEREBRAL VASCULAR ACCIDENT, Endometrial Cancer, cerebrovascular diseases Hepatitis,Glaucoma, Cataracts,Macular degeneration, Cardiovascular disease, Lung disease, Enlarged prostate, Alzheimer's disease, Dementia, Tach Disease, Shingles, Lung Cancer, Leukemia Lymphoma, Lung Cancer, Mesothelioma Asbestos, Ovarian Cervical Uterine Cancer, Skin Cancer, Brain Tumor, H.P.V TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5. HIV,Arthritis, Fibromyalgia, Fluoroquinolone Toxicity, Cervical Cancer, Colo-rectal Cancer, Blood Cancer, SYPHILIS, Diabetes, Liver / Inflammatory kidney, Epilepsy.

Racheal Luis said...

Dr. Ehimare has really made me so much believe in him by getting me cured of Herpes with his herbal medicine. I have been a Herpes virus patient for some time now, I have been running here and there looking for help/cure but none could help. I ran into a testimony by someone who testified how she was cured of a terrible disease by Dr. Ehimare, so I decided to contact the herbal doctor. I explained to him, and he said he can cure me. We started the process and he prepared herbs and sent them to me in my country and gave me directions on how I am to use them. I followed his directions and now To God be the glory he could cure me with his herbal mixture. I really appreciate you Dr. Ehimare for bringing back happiness to my life again. thanks you so much friends that has join me to thank Dr. Ehimare for what he has actually done for me i pray to you all for a good life and property, his contact. Email address drehimare3@gmail.com , via whats-app +1 (267) 691-1087 Thanks Dr. Ehimare for your help in my life and family... and most especially to you Dr. THANKS.