tag:blogger.com,1999:blog-196334975274806517.post6412614317164635352..comments2024-03-28T06:11:20.882-06:00Comments on Cooling Inflammation: Biofilm Transformation, Helicobacter, KlebsiellaDr. Art Ayershttp://www.blogger.com/profile/01727664149735013259noreply@blogger.comBlogger41125tag:blogger.com,1999:blog-196334975274806517.post-28353251077851644422015-06-04T23:07:01.259-06:002015-06-04T23:07:01.259-06:00hi Dr Ayers
Not sure if reading this correctly. ...hi Dr Ayers<br /><br />Not sure if reading this correctly. Could taking Lactoferrin supplements assist in the management of Crohns disease by eliminating kP? I was diagnosed with Crohns a few years ago and found the low carb / SCD to be the best way to stay in remission.<br /><br />Only just discovered your blog. Very grateful for the work you do.<br /><br />thanks<br />RM<br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-87186893196451708492015-02-22T12:16:34.755-07:002015-02-22T12:16:34.755-07:00This blogpage is so relevent to me!I have KP livin...This blogpage is so relevent to me!I have KP living in my gut and have been attempting to get its numbers down for the past 2 years, with some success.<br />Any help you can give me would be very helpful and very much appreciated.<br />I get no support from my own GP as the KP was found using a private doctor and lab by myself after I had been suffering from this same issue since my early teens and getting steadily worse by following NHS advice.She therefor does not recognise the test result or any of the methods I am using to combat it.I am on my own with it basically.I do have online support from a facebook group of patients of a Dr Sarah Myhill,an enviromental Dr from Wales, but she has too many patients on her books and isn't accepting any more.I haven't been able to gain a career due to this problem and we don't have any money to spare in trying to find a private doctor who will work with me on it,or to pay for any health insurance which would cover it as our household finances are extremely stretched already.Thankyou for posting this information.<br /><br />Melanie StephenMelnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-59355792639491709682015-01-01T10:43:24.401-07:002015-01-01T10:43:24.401-07:00Dr. Ayers,
I stumbled upon your website while rese...Dr. Ayers,<br />I stumbled upon your website while researching my recently diagnosed ankylosing spondylitis. I've been on a paleo diet for two years with little success. I started fermenting my own vegetables for Hashimotos. They are somewhat helpful. Now I'm adding resistant starches (PHD). My doctor put me on Embrel and LD Naltrexone two weeks ago and just from a day spent on your website, I think suppressing my immune system is the wrong approach. Would you agree?<br /><br />VickiAnonymoushttps://www.blogger.com/profile/04716875428583318898noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-70790916440139197452012-08-02T05:06:56.308-06:002012-08-02T05:06:56.308-06:00I found your article when I started wondering abou...I found your article when I started wondering about whether there is a connection between a virus I had while in Alaska, and the now chronic inflammation of my esophagus and ulcers. Following a violent stomach virus, I was diagnosed with klebsiella uti, and took antibiotics, I had chronic uti's all of my life until after the birth of my son, when they seemed to miraculously go away. However, following this virus, they became chronic again, and still are. Around the same time, I developed a stomach ulcer and gerd, and went on a 5 month course of Prilosec. I seemed to heal ok, but then 2 years later, I developed the same condition again. Ulcer, gerd, and still chronic uti's. When I was scoped 2 years ago, I was told H pylori was not an issue. This time the recommended medical regime seemed to heal the ulcer, but not the inflammation of my esophagus and gerd. I'm only 43, and am concerned about this continuing because I know the cancer risks. I have been taking some things recommended by my health food store, such as neem, licorice, orange peel, probiotics, etc. I get the most relief from chewing on cardamom seeds, strangely. Do you have any thoughts on all of this?TAPnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-13617690593249169952011-09-14T18:36:10.278-06:002011-09-14T18:36:10.278-06:00Hey Doc,
Have a lengthy history of crohn's, b...Hey Doc,<br /><br />Have a lengthy history of crohn's, but have been managing things well with your diet suggestions. i still have some lingering symptoms, primarily looser stools and am always looking for alternative treatments. read a study using mastic gum for crohns which looks interesting. i do have h pylori, but never treated it based primarily on your suggestions that it may be helping to keep my immune system in check. any thoughts about the use of mastic? it doesn't seem to be a great h pylori killer and I would be interested to see if it improves any of my crohns symptoms, but am slightly concerned that it could still knock it out. thanks in advance.chemisthttps://www.blogger.com/profile/18031153394028163705noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-48600896465404490482011-04-12T07:25:02.846-06:002011-04-12T07:25:02.846-06:00Hi Dr. Ayers,
I found your blog last night throug...Hi Dr. Ayers,<br /><br />I found your blog last night through Stephan Guyenete's site and am pretty sure my wife is about to divorce me if I don't stop reading and get some sleep...<br /><br />I have ankylosing spondylitis and after experimenting for 5 years with the no-starch diet have ended up with a diet almost exactly like the one you recommend.<br /><br />I've had great success with my diet but was recently reading on roadback.org and considering antibiotics to augment my dietary treatment of AS. Not sure if it's overkill at this point since I've had such good success using my version of the NSD. Do you have any thoughts on using antibiotics to treat AS?<br /><br />Second: I've always been concerned about using probiotics as I'm not sure if K.p would be given some sort of advantage as you introduce other bacteria. Irrational fear? Probably, but now that I've gotten my flares under control I'm a little reluctant to mess with a relatively good thing. Pain is a cruel teacher. Should I add probiotics to my regimen?<br /><br />I'm a little obsessed about spreading the word on dietary treatment for AS and have started a blog (www.sickopportunity.com) to do my part for the AS community. Was wondering if you could help point me in the right direction in regards to scientific papers and researchers who are studying Klebsiella, AS, etc. Pubmed and Google Scholar are great, but lots of wading through not so good stuff to find the gems.<br /><br />My email address is bobconnors@gmail.com if there's any way you'd consider emailing me a few primary sources or other advice.<br /><br />Thanks so much for this fantastic blog!<br /><br />Best,<br />Bob Connors<br />www.sickopportunity.comBob Connorshttp://www.sickopportunity.com/noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-77044412289895270812011-03-01T15:28:08.902-07:002011-03-01T15:28:08.902-07:00Steve,
My first impression is that you have tried ...Steve,<br />My first impression is that you have tried half of the cure. The medical community seems unaware of recent research showing the complexity of the normal gut flora. You identified the problem as inappropriate use of antibiotics to treat acne and changed your diet.<br /><br />Unfortunately, you didn't successfully recruit the hundred plus new species of bacteria needed to get your colon flora and its immune system functioning. That is the part of the immune system needed to suppress immune system attack on the gut. Loss of these bacteria is typical of the symptoms of Crohn's.<br /><br />The quick fix would be a fecal transplant. Slow and steady eating of diverse veggies with clinging soil bacteria will build up the needed gut flora community to get your immune system functioning properly.<br /><br />More antibiotics to fix the Helicobacter would seem to only contribute to the problems. The presence of H. pylori may be keeping your Crohn'-like symptoms in check.<br /><br />Let me know what happens.Dr. Art Ayershttps://www.blogger.com/profile/01727664149735013259noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-58106870363654840652011-03-01T11:58:47.821-07:002011-03-01T11:58:47.821-07:00Dr ayers,
I would really appreciate any insights ...Dr ayers, <br />I would really appreciate any insights on this…I've battled chronic diarrhea for years, eventually diagnosed with crohns , due to the presence of mild chronic inflammation thru out my small bowel (from capsule endoscopy). I've been working with a functional medicine MD and recently had a stool test that showed h.pylori, no growth of e coli or lactobacillus, and large amounts of growth of alpha/gamma heamolytic strep. All this despite, following a paleo-ish diet and tons of fermented food. I was on antibiotics for years (acne), which I think lead to my present state. My doc wants to treat the h. pylori with conventional antibiotics, but I'm a little gun shy given the current state of health of my gut and past history. Any thoughts?<br /><br />Thanks so much in advance,<br />SteveAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-27253971205035739682011-02-11T08:06:29.361-07:002011-02-11T08:06:29.361-07:00Dr. Ayers ; Can you respond to my last comments wh...Dr. Ayers ; Can you respond to my last comments when you have time.<br />Thanks ; doctors are of very little help when it comes to these kind of problems<br /><br />PaulPaulnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-57845590556371579562011-02-10T10:07:48.579-07:002011-02-10T10:07:48.579-07:00Paul,
I use romaine (most nutritious) lettuce lea...Paul,<br /><br />I use romaine (most nutritious) lettuce leaves for sandwich wraps instead of bread.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-17250348043307814062011-02-10T08:29:04.751-07:002011-02-10T08:29:04.751-07:00Dr. Ayers I was also on antibiotics
since late Aug...Dr. Ayers I was also on antibiotics<br />since late August of last year.<br />Once I completed them, I developed a C Diff infection.<br /><br />PaulPaulnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-45318452754325564952011-02-10T08:25:38.700-07:002011-02-10T08:25:38.700-07:00Dr. Ayers , Thanks for the response for the diver...Dr. Ayers , Thanks for the response for the diverticulosis. You cautioned me about grains before ; which I have been consuming for many years through bread products. What type of breads shuld be used for a sandwich ?Paulnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-82025856736422092212011-02-09T20:31:05.360-07:002011-02-09T20:31:05.360-07:00Paul,
My first suspicion with any disfunction of t...Paul,<br />My first suspicion with any disfunction of the colon would involve nutrition to the colon cells and signaling for colon development. Colon nutrition is derived from the short chain fatty acids produced by anaerobic fermentation of soluble fiber by gut flora. Signaling is also from the gut flora.<br /><br />Diverticulosis is frequently accompanied by constipation, which is a deficiency of gut bacteria. There is also a weak association between a decrease in symptoms with increasing dietary fiber. Both of these point to gut flora as the source of the problem.<br /><br />It would seem that the anti-inflammatory diet that I recommend on this site would be an obvious starting point. Get your serum vit.D checked and make sure that you are eating a wide variety of fresh vegetables to provide needed colon bacteria, as well as soluble fiber. There are hundreds of different species of gut bacteria and hundreds of different plant polysaccharides that are soluble fiber. Avoid grains.<br /><br />Let me know how this works out.Dr. Art Ayershttps://www.blogger.com/profile/01727664149735013259noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-44969162346474110022011-02-09T19:14:39.333-07:002011-02-09T19:14:39.333-07:00Doctor Ayers : What can you recommend for divertic...Doctor Ayers : What can you recommend for diverticulosis ?Paulnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-10881712927549713842010-12-03T13:25:46.024-07:002010-12-03T13:25:46.024-07:00Dr Ayers,
Thanks for you additional input.
This ...Dr Ayers,<br /><br />Thanks for you additional input.<br /><br />This part makes me a little nervous... "the restructuring of the tissue reinforces the condition". <br /><br />Hopefully I have not done irreversible damage to my cells involved in this. It's only been about 3 months. I am bent on 'fixing' this problem. I cannot accept "just living with it". <br /><br />I will cut down even further on grains, even sprouted. The most fruit I have is a handful of blueberries (normally eaten with heavy cream) or maybe a half of a very small banana with cream. Sometimes a slice of watermelon but not very often.<br /><br />The H.pylori dealio is pretty confusing to me. I am just trying to figure out what to eat/what not to eat to restore normal gut flora. So thanks very much for your comments.<br /><br />Regards,<br />JackJackhttps://www.blogger.com/profile/03925820413280991430noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-63144655883828867262010-12-02T11:15:51.635-07:002010-12-02T11:15:51.635-07:00Jack,
Starch is starch and all grains are predomin...Jack,<br />Starch is starch and all grains are predominantly starch. I have stopped routinely eating breads to avoid insulin spikes. Saturated fats are healthier and more satisfying. Plenty of veggies are better than fruit, to avoid fructose, sucrose and starch.<br /><br />I think that it is clear from many studies that GERD is not caused by Helicobacter pylori. In fact, Hp, because it inhibits stomach acid production, is protective for GERD. GERD frequently results from antibiotic elimination of Hp in the treatment of ulcers.<br /><br />GERD is associated with a different bacterium in animal studies. I think that GERD is parallel with ear infections. Ear infections occur when the Eustachian tube is obstructed by inflammation of the surrounding tissue. In GERD, the inflammation stops the proper collapse of the base of the esophagus so the stomach acid can slosh or be pushed upward. The difference, is that bacteria growing in the dammed up middle ear contribute to the ear infection, whereas infection/inflammation of the esophagus keeps it from closing when acid builds up.<br /><br />After GERD is established, I think that it is like asthma, in which the restructuring of the tissue reinforces the condition. It seems important to avoid the mechanical conditions that bring acid in contact with the esophagus while returning the rest of the GI tract to normal. That suggests small meals, empty stomach at bed time and avoiding postures that permit the acid to flow upward.<br /><br />This isn't very satisfying, but I hope it is a little helpful.Dr. Art Ayershttps://www.blogger.com/profile/01727664149735013259noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-83247220222640220432010-12-02T10:06:39.872-07:002010-12-02T10:06:39.872-07:00Dr Ayers,
Thank you very much for taking the time...Dr Ayers,<br /><br />Thank you very much for taking the time to respond. I have read your reply a few times and I think I understand. But just to make sure...<br /><br />It seems that what you are saying is:<br /><br />1. starchy carbs pose more of a problem for me than 'carbs' in general, like fruits and veggies.<br /><br />2. fruits and veggies will produce a wider array of gut bacteria, and this could be beneficial to me because H.p. could feed off of a normalized level of hydrogen, rather than looking for starch and/or glucose.<br /><br />That leads to me to think that when I went low carb, the diversity of gut bacteria was dramatically reduced, forcing resident H.p. to scavage for other sources of energy, causing a change in the normal pattern of H.p. and thereby an overgrowth as a result. This is then causing my esophagus sphincter to get cranky.<br /><br />Is that pretty accurate or am I out in left field?<br /><br />The odd thing is that on my old diet, I ate tons and tons of carbs, including white breads, potatoes, rice, pastas, sugars… all kinda bad stuff, and I didn’t have heartburn. Don’t get me wrong, I feel better in all other respects in the last 4 months, and I’ve lost 11 pounds and gained significant muscle mass.<br /><br />Chris Kresser recommends that I do the urea breathe test to confirm an H.p. infection and take HCL tablets with my meals. I would have to order the kit from my physician so it will take a bit before I can get the results back.<br /><br />In the meantime, would you say it's best to increase my veggie intake, as well as more fruits?<br /><br />Also, do sprouted grain breads count as 'starchy' carbs? I do not eat white flour products anymore, but I do have a piece or two of sprouted bread daily for a vehicle for pasture butter.<br /><br />Sorry for such a long winded post. I am also seeing my physician but people like you with the right mind for this sort of thing is really a staple resource for me to be able to get to the bottom of this annoying issue.<br />I really appreciate your unique perspective Dr Ayers. <br /><br />Thanks,<br />Jack K.Jackhttps://www.blogger.com/profile/03925820413280991430noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-37782050341345922022010-11-29T16:19:26.123-07:002010-11-29T16:19:26.123-07:00Jack,
I don't think that the issue is carbs, b...Jack,<br />I don't think that the issue is carbs, but rather starch versus soluble fiber, e.g. pectin or inulin in fruits and vegetables. Normal stools require a large volume of packed gut bacteria. Growth of gut bacteria is dependent on protein, fat and polysaccharides that reach the colon. If the bacteria in the colon are diverse enough (roughly 100 different species of bacteria), then anything animal or vegetable that is tossed in will be digested. In the absence of diverse bacteria, some of the material will pass through in the stool.<br /><br />On a low carb diet without many veggies, little will pass through to feed the bacteria and very small volume of stools will be produced. Stools are packed bacteria, so most of the stool volume comes from plant polysaccharides that human cells don't produce enzymes to digest, i.e. everything except starch. <br /><br />Mucin is produced independent of dietary carbs. Without mucins, you would be in trouble, but I don't think that high or low carbs will alter the mucins. I was not convinced by the article that you cited.<br /><br />Hydrogen production by gut bacteria is a necessary part of gut function. I personally don't think that H.p. is a problem when it is getting mostly hydrogen for its energy. I think the problems occur when too much starch is being digested and glucose is abundant.<br /><br />Thanks for the comments and questions.Dr. Art Ayershttps://www.blogger.com/profile/01727664149735013259noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-44639791788708031722010-11-29T12:47:20.304-07:002010-11-29T12:47:20.304-07:00Hi. Are my posts getting deleted by the system? I ...Hi. Are my posts getting deleted by the system? I see them posted when I submit, but then they disappear right away.Jackhttps://www.blogger.com/profile/03925820413280991430noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-36842914793740911322010-09-07T15:51:25.665-06:002010-09-07T15:51:25.665-06:00"Bran is not healthy, it merely produces mine..."Bran is not healthy, it merely produces mineral deficiencies."<br /><br />Is this caused by phytic acid? This acid is found in many substances other than bran, I think.<br /><br />Can you explain further why bran is not good? I eat some oat bran, to feed the flora, at least this is what I think! Thank you again.MasKnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-68550925264868617922010-09-07T01:50:57.178-06:002010-09-07T01:50:57.178-06:00Sandra,
I wouldn't recommend wheat and especia...Sandra,<br />I wouldn't recommend wheat and especially not bran, since they both produce additional problems.<br /><br />Klebsiella is associated with ankylosing spondylitis, but I am not sure how they are connected. It could be via LPS or other bacteria components or it could be through the impact of these compounds on the gut immune system.<br /><br />I don't think that probiotics can impact the Klebsiella directly, since they are in different parts of the gut, but the probiotics may alter the composition of the immune system and alter the course of the disease.<br /><br />It is also possible that stripping the gut biofilms with PEG, EDTA and enzymes, as described in another of my articles, would provide an opportunity to recreate a healthier gut flora. Some people with related conditions show relief from the total bowel irrigation that precedes a colonoscopy, because it also strips away the biofilms.<br /><br />He might also benefit from the Eades diet that I explain elsewhere. That diet approach involves another treatment with milk whey that may provide a transition to a low carb diet that is healthier in general and may also treat AS.<br /><br />Please read my other articles on reestablishing gut flora to avoid the misconceptions about fiber. Bran is not healthy, it merely produces mineral deficiencies. Healthy fiber that nourishes gut flora is plant polysaccharides that can be digested by bacteria in the colon, e.g. pectin and inulin. I would recommend for AS to avoid grains, starch and sugar. Look at my anti-inflammation diet. It is readily adapted for diabetics, gluten intolerance and other diseases that benefit from low carbs. Most people find it very easy to shift to it, since it is very satisfying.<br /><br />Thanks for your questions/comments. Let me know if I can provide more info or suggestions, and tell me how it works out.Dr. Art Ayershttps://www.blogger.com/profile/01727664149735013259noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-3868156134924211942010-09-07T01:33:01.961-06:002010-09-07T01:33:01.961-06:00MasK,
Diet-based chronic inflammation decreases th...MasK,<br />Diet-based chronic inflammation decreases the ability of the skin to produce vit.D. Thus, people exposed to high levels of solar radiation, e.g. Southern California or Florida, frequently have vitamin D deficiencies, because of bad diets. The anti-inflammation diet that I recommend fixes the diet and permits vit.D production. Vit.D3 supplements also lower inflammation and permit a return to solar production of vit.D in the skin.<br /><br />Dysfunctional gut flora can produce inflammation in a variety of ways, e.g. vitamin and mineral malabsorption, or dysruption of normal immune function via the GALT.<br /><br />Thanks for the question.Dr. Art Ayershttps://www.blogger.com/profile/01727664149735013259noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-4400306625371919422010-09-04T03:46:30.076-06:002010-09-04T03:46:30.076-06:00Hello Dr Ayers.
Can you explain the following :
&...Hello Dr Ayers.<br />Can you explain the following :<br /><br />"Sun exposure won't help with her vit.D deficiency until she lowers her diet-based inflammation. Increasing the saturated fat in her diet may improve her tolerance of fish oil. She is probably not eating enough calories, because she lowered her carbs, but didn't increase her saturated fat consumption to compensate for the lost calories."<br /><br />What is the link between the inflammation and the capacity of using or processing Vit D?<br /><br />And what is the link between gut flora and this capacity?<br /><br />Thank you very muchMasKnoreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-40751850472830118502010-09-03T03:52:30.202-06:002010-09-03T03:52:30.202-06:00Hello! I always love reading your posts, thank you...Hello! I always love reading your posts, thank you for sharing this information. Before i read this post i thought that it was klebsiella LPS leaking from the gut that people with AS react to. <br /><br />Do you think that eating good live probiotics can take away klebsiella biofilms? Or do you think that some food can help take them away? <br /><br />I have a friend with ankylosing spondylitis, but he refuses to go on a no starch diet. I also think that the diet isn't so good since it doesn't fix the problem. The bacteria is still there, just waiting to have some food. <br /><br />I know that eating wheat and oat bran raises bifidobacteria, but is there something more he can do besides that? He has started to eat more fibre like whole grain rice, wheat bran and less sugar. He also eats some home made yoghurt with "lactobacillus acidophilus La-5, bifidobacterium lactis bb-12, streptococcus thermophilus and lactobacillus delbrueckii subsp. bulgaricus". <br /><br />I am grateful for any thoughts you might have on this. <br /><br />SannaAngelhttps://www.blogger.com/profile/06019156585843311327noreply@blogger.comtag:blogger.com,1999:blog-196334975274806517.post-32287273675193109712010-09-02T22:43:41.315-06:002010-09-02T22:43:41.315-06:00Jack C.,
Ulcers are usually the result of H. pylor...Jack C.,<br />Ulcers are usually the result of H. pylori, as you indicate, but there is currently some speculation that most people live with H. pylori and have no symptoms. That suggests that the ulcers and cancer associated with H. pylori result from a disruption of the normal environment in which the H. pylori normally lives peacefully.<br /><br />Your wife has a lot of food intolerance and can't take vit.D3. This indicates that her gut flora is messed up. That is consistent with prior antibiotic use.<br /><br />I think that she would improve with probiotics and development of her gut flora, as I suggest elsewhere on this blog. She is probably also constipated and may suffer from intestinal yeast infection.<br /><br />She needs to persistently expand her diet and improve her tolerance to foods, i.e. her gut flora diversity, by gradually increasing exposure to the foods that cause digestive problems. Her bowel movements should gradually normalize. She should eliminate the use of laxatives. Antibiotics will make her long term cures harder. She also needs to increase her physical activity and build muscle strength.<br /><br />Sun exposure won't help with her vit.D deficiency until she lowers her diet-based inflammation. Increasing the saturated fat in her diet may improve her tolerance of fish oil. She is probably not eating enough calories, because she lowered her carbs, but didn't increase her saturated fat consumption to compensate for the lost calories.<br /><br />I think that her ulcers are just symptoms of her disrupted gut flora and eating better can eliminate all of her problems.<br /><br />Let me know of her progress. Continue to ask questions and read more of my articles.Dr. Art Ayershttps://www.blogger.com/profile/01727664149735013259noreply@blogger.com